Nicholas Biddle (1786-1844) was one of the most prominent men in early 19th century America, best known as President of the Second National Bank of the United States. Many of his family members were also prominent to their contemporaries and to history, including Nicholas's brother, Commodore James Biddle (1783-1848), who served in the Navy for decades and worked to open up trade with Asia. The Biddle family papers, 1747-2011, consist largely of original manuscript documents from a number of Biddle family members, notably Nicholas Biddle (1786-1844), Commodore James Biddle (1783-1848), Letitia Glenn Biddle (1864-1950), Charles J. Biddle (1890-1972) and Katharine Legendre Biddle (1893-1973), and Nicholas Biddle, Jr. (1917-2013). In addition, there are some secondary-source materials pertaining to the Biddle family and the administration of Andalusia, the family's ancestral home.