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Papers of Raymond E. Vanderlinde

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Held at: Science History Institute Archives [Contact Us]315 Chestnut Street, Philadelphia, PA 19106

This is a finding aid. It is a description of archival material held at the Science History Institute Archives. Unless otherwise noted, the materials described below are physically available in their reading room, and not digitally available through the web.

Overview and metadata sections

Raymond E. Vanderlinde was an American clinical chemist. He was a noted expert on enzymes and had a special interest in the treatment of diabetes. Vanderlinde was born in Newark, New York in 1924. He was educated at Syracuse University, where he earned his A.B in Science Education (1944) and his M.A. in Science Education (1945). After a brief stint as a high school science and math teacher at Gorham Central School in Gorham, New York, he returned to Syracuse, where he earned his M.S. in Organic Chemistry (1947) and his Ph.D. in Biochemistry and Physiology (1950). He was the first graduate student to earn his Ph.D. through Syracuse University's College of Medicine.

After earning his Ph.D., Vanderlinde served as Assistant Professor, then Associate Professor of Biochemistry at the University of Maryland School of Medicine in Baltimore, Maryland (1950-1957). In 1957, he accepted a position at Syracuse Memorial Hospital in Syracuse, New York as its first clinical chemist and Director of Clinical Laboratories (1957-1962). From 1962 to 1965, Vanderlinde served as Associate Laboratory Director and Clinical Chemist at Memorial Hospital in Cumberland, Maryland. In 1965, he accepted a position at the New York State Department of Health's Division of Laboratories and Research, where he served as Director of Clinical Chemistry (1965-1977). From 1977 until his retirement in 1990, Vanderlinde served as Professor of Pathology and Laboratory Medicine and Director of Clinical Chemistry at Hahnemann Medical College in Philadelphia, Pennsylvania.

Vanderlinde was a member of several professional organizations, including the American Association for Clinical Chemistry (AACC) and the American Chemical Society (ACS). He was particularly active with the AACC, where he was a noted advocate for professional standards in clinical chemistry. He served the AACC in several capacities, including as Chairman of the New York Upstate Section (1959-1960, 1966-1967) and as a member of the Board of Directors (1979-1981).

Vanderlinde authored numerous journal articles over the course of his career, principally in the areas of enzyme measurement and standardization, enzyme reference materials, laboratory evaluation, and quality control. He also wrote about the history of the AACC and clinical chemistry. In 1985, he was the recipient of the AACC Award for Outstanding Contributions through Service to Clinical Chemistry as a Profession.

Raymond E. Vanderlinde passed away on July 14, 2007.

Sources

American Association for Clinical Chemistry. "Raymond E. Vanderlinde, Ph.D." Raymond E. Vanderlinde, PhD | AACC.org

Medical Alumni Association of the University of Maryland. "In Memoriam: Fall 2007." MAA - The Bulletin -Fall 2007 - In Memoriam (medicalalumni.org)

Papers of Raymond E. Vanderlinde, Science History Institute Archives, Philadelphia, Pennsylvania.

Vanderlinde, Raymond E. A Century of Healthcare and Medical Education from the Viewpoint of a Clinical Chemist. Washington, D.C.: AACC Press, 2007. Vanderlinde Book_FM.pdf (aacc.org)

The Papers of Raymond E. Vanderlinde contain the professional papers of American clinical chemist Raymond E. Vanderlinde. Arranged mostly chronologically by year, the files in this collection document Vanderlinde's professional career as a clinical chemist, including his stints with the University of Maryland School of Medicine, Syracuse Memorial Hospital, Memorial Hospital in Cumberland, Maryland, the New York State Department of Health, and Hahnemann Medical College. Vanderlinde's activities with the American Association for Clinical Chemistry are also documented in this collection. Small numbers of files documenting Vanderlinde's graduate school career at Syracuse University, conferences he attended, and his activities with other professional organizations are also preserved here.

The contents of the files in the Papers of Raymond E. Vanderlinde consist of a wide variety of materials. Correspondence and reprints are the most common materials found in this collection. Smaller, but noticeable, amounts of minutes, grant applications, preprints, and notes are also present in this collection. Small amounts of other miscellaneous materials, including, but not limited to, data, reports, proposals, and graduate school theses are preserved here as well.

The Papers of Raymond E. Vanderlinde were donated to the Science History Institute (formerly the Chemical Heritage Foundation) by Raymond E. Vanderlinde in July 2000.

The Papers of Raymond E. Vanderlinde were processed by Andrew Mangravite in March 2017.

Publisher
Science History Institute Archives
Finding Aid Author
Finding aid created by Andrew Mangravite and encoded into EAD by Kenton G. Jaehnig.
Finding Aid Date
2017
Access Restrictions

There are no access restrictions on the materials for research purposes and the collection is open to the public.

Use Restrictions

The Science History Institute holds copyright to the Papers of Raymond E. Vanderlinde. The researcher assumes full responsibility for all copyright, property, and libel laws as they apply.

Collection Inventory

Vanderlinde, Raymond E. "Synthesis of Derivatives of Stilbestrol and Hexestrol", M.S. Thesis, Syracuse University, 1947.
Box 1 Folder 1
Physiology Experiments, Syracuse University, 1948.
Box 1 Folder 2
University of Maryland - correspondence, re: synthetic estrogens and other topics, 1948-1957, 1961, 1965.
Box 1 Folder 3
Vanderlinde, Raymond E. "The Inactivation of Estrogens", Ph.D. Dissertation, Syracuse University, 1950.
Box 1 Folder 4
University of Maryland - Public Health Service Research Grant, 1953-1959.
Box 1 Folder 5
Medical Course, School of Medicine, University of Maryland, 1955-1956.
Box 1 Folder 6
Syracuse Memorial Hospital - Graduate School, 1954-1974.
Box 1 Folder 7
Vasington, F.D. - Ph.D. Thesis, School of Medicine, University of Maryland (Raymond E. Vanderlinde was Vasington's thesis advisor.), 1955.
Box 1 Folder 8
American Association for Clinical Chemistry - New York Upstate Section, 1957-1962, 1969, 1976, 1988.
Box 1 Folder 9
American Association for Clinical Chemistry - New York Upstate Section - scrapbook, 1957-1960.
Box 1 Folder 10
Syracuse Memorial Hospital - carbon copy letters, 1958-1961.
Box 1 Folder 11
American Association for Clinical Chemistry - Early Materials, 1958-1970.
Box 1 Folder 12
Syracuse Memorial Hospital - Nurses' Directions, 1959.
Box 1 Folder 13
Syracuse Memorial Hospital - Clinical Lab Nurses' Manual, 1959.
Box 1 Folder 14
Quality Control and Study - Gen. and Enzymology - reprints, data, lecture overheads, minutes of meetings, 1959-1976.
Box 1 Folder 15
Historical Development of Clinical Chemistry - classic reprints, 1956-1998.
Box 1 Folder 16
Division of Laboratories and Research (DL&R), Albany - correspondence, 1960-1976.
Box 1 Folder 17
Normal Values Research - reprints and data, 1960-1983.
Box 1 Folder 18
American Association for Clinical Chemistry - Historical - correspondence and internal documents, 1961-1999.
Box 1 Folder 19
Memorial Hospital, Cumberland, Maryland - Laboratory Bulletin, Volume 1, Numbers 1-3; Volume 2, Numbers 1-2, 1962, 1964.
Box 1 Folder 20
Medical Technology Course, Allegany Community College, Cumberland, Maryland - correspondence and course outlines, 1962-1977.
Box 1 Folder 21
American Association for Clinical Chemistry - New York Upstate Section - correspondence, reminiscences, minutes of meetings (Folder 1 of 3.), 1964-1976.
Box 1 Folder 22
American Association for Clinical Chemistry - New York Upstate Section (Folder 2 of 3.), 1964-1976.
Box 1 Folder 23
American Association for Clinical Chemistry - New York Upstate Section (Folder 3 of 3.), 1964-1976.
Box 1 Folder 24
Division of Laboratories and Research - New York State Department of Health, 1965-1975, 1998.
Box 1 Folder 25
Toxic New York State Department of Health, Division of Laboratories and Research "Drugs of Abuse" - includes "Desk Reference on Drug Abuse", 1966-1971.
Box 2 Folder 1
Inherited Metabolic Disease - Phenylketonuria (PKU)-related items, 1966-1976.
Box 2 Folder 2
Division of Laboratories and Research - correspondence, reprints, notes, and salary-related items, 1968-1975.
Box 2 Folder 3
Division of Laboratories and Research - New York State Department of Health - Rules and Regulations, 1968-1973, 1998.
Box 2 Folder 4
College of American Pathologists (CAP) Consent Decree (An anti-trust action was brought by the Department of Justice against the College of American Pathologists for alleged price-fixing and boycotting of non-members.), 1969, 1981.
Box 2 Folder 5
Clinical Chemistry Historical and Basic Principles - reprints, 1970-1975.
Box 2 Folder 6
National Conference on Professional Testing - correspondence, minutes of meetings, reports, 1971.
Box 2 Folder 7
Food and Drug Administration (FDA) - correspondence, documents, minutes of meetings, 1972-1982.
Box 2 Folder 8
Clinical Enzymology Meetings, 1972-1984.
Box 2 Folder 9
Drugs of Abuse - miscellaneous materials including "Performance Testing in Drug Abuse Screening" by Raymond E. Vanderlinde, 1972-1995.
Box 2 Folder 10
Korea (Korea Institute of Science and Technology) - correspondence, trip materials, and preprint of Raymond E. Vanderlinde's presentation, 1973-1974.
Box 2 Folder 11
Korea - Talks - On Enzymology, Testing Standards, and Government Regulation given by Raymond E. Vanderlinde while a Visiting Scientist at Korea Institute of Science and Technology, 1973-1975.
Box 2 Folder 12
Research Grants - continuing Department of Health, Education, and Welfare (HEW) applications ("Optimized Inter-laboratory Enzyme Assays: LDH, ASPAT".), 1973, 1976.
Box 2 Folder 13
Historic Quality Control - reprints of articles concerning quality control testing in labs, 1973-1978.
Box 2 Folder 14
Revised Grant Applications - Chromium/Diabetes/OPT LDH ASPAT, 1973-1979.
Box 2 Folder 15
Food and Drug Administration - Product Class Standards, Labelling Requirements (Raymond E. Vanderlinde served on the Advisory Committee on Diagnostic Problems.), 1973-1982.
Box 2 Folder 16
American Association for Clinical Chemistry - Standards Committee - correspondence, programs, minutes of meetings, 1975-1981.
Box 2 Folder 17
Division of Laboratories and Research - correspondence, memos, preprints, re: proficiency testing, 1975-1976.
Box 2 Folder 18
American Association for Clinical Chemistry - Performance Evaluation Committee - correspondence, proposals, 1976-1977.
Box 2 Folder 19
Commission on Accreditation in Clinical Chemistry (COMACC) - History and Records, 1976-1990.
Box 2 Folder 20
College of American Pathologists (CAP) Conference: "Analytical Goals in Clinical Chemistry", Aspen, Colorado, 1976 - abstracts, 1976.
Box 2 Folder 20b
Grant - Enzymes - application and research plan, 1977.
Box 2 Folder 21
American Association for Clinical Chemistry - Philadelphia Section - correspondence and section documents (Folder 1 of 2.), 1977-1980.
Box 2 Folder 22
American Association for Clinical Chemistry - Philadelphia Section (Folder 2 of 2.), 1977-1980.
Box 2 Folder 23
Hahnemann Medical College - miscellaneous materials including a history of Hahnemann Hospital, 1976-1989.
Box 2 Folder 24
Speculation and Reprints - by Raymond E. Vanderlinde and others ("Speculation" concludes that "Diabetes is a Multifactorial Disease".), 1978-1985.
Box 3 Folder 1
American Association for Clinical Chemistry - Philadelphia Section and Pennsylvania State Advisory Committee - includes history of the section, 1978-1984.
Box 3 Folder 2
National Committee for Clinical Laboratory Standards (NCCLS) Council - Historical, 1978-1996.
Box 3 Folder 3
Course in Lab Medicine - Historical - given at Hahnemann Hospital, 1978, 1990.
Box 3 Folder 4
Path Seminar - Chromium Review, 1978-1979.
Box 3 Folder 5
Board of Directors - American Association for Clinical Chemistry, 1979.
Box 3 Folder 5b
Licensure, Professional Relations, and College of American Pathologists (CAP) - includes draft proposal and xerox of State Assembly bill, 1978-1980.
Box 3 Folder 6
Kayne, F.J. - Department of Health, Education, and Welfare (HEW) grant application ("Isolation and Role of Chromium Compounds in Urine"), 1979.
Box 3 Folder 7
Related Materials

See also Box 3 Folder 12.

Kayne, F.J. - Two Proposals - to National Science Foundation (NSF) and Department of Health, Education, and Welfare (HEW) on chromium and metalloimmunoassay and direct analysis of trace elements, 1979, 1982.
Box 3 Folder 8
Chromium Grant Renewal – Department of Health, Education, and Welfare (HEW) grant - "Relationship of Tissue Levels of Chromium to Diabetes", 1979.
Box 3 Folder 9
Sherbrooke, Quebec, Canada (Symposium on "Chromium in Nutrition and Metabolism"), 1979.
Box 3 Folder 10
Urine Chromium Identification - correspondence, reprints, data, 1980-1983.
Box 3 Folder 11
American Chemical Society (ACS) Board Committee on Clinical Chemistry - correspondence, minutes, history, 1980-1990.
Box 3 Folder 12
Joint with Joslin Clinic - 1980-1982/American Diabetes Association (ADA) Feasibility Grant Program - Raymond E. Vanderlinde. "Effects of Urinary Peptides on the Pyruvate Dehydrogenase Reaction" - application and research plan (Application not approved by ADA.), 1982.
Box 3 Folder 13
Chromium Peptide - research and draft of a paper, 1980-1982.
Box 3 Folder 14
Sunderman Monthly PT Prog. - Proficiency Test Service, 1981-1984.
Box 3 Folder 15
Annals of Clinical and Laboratory Science/Sunderman, 1982-1984, 1993.
Box 3 Folder 16
Glucose Tolerance Factor (GTF) - four reprints, 1982-1985.
Box 3 Folder 17
Chromium 1982 - reprints and presentations by Raymond E. Vanderlinde and others, 1982.
Box 3 Folder 18
Larner, Joseph (University of Virginia School of Medicine) - correspondence, research notes, 1982-1983.
Box 3 Folder 19
Multiphasic Laboratory Screening and Profiling - program and Raymond E. Vanderlinde notes, 1982.
Box 3 Folder 19b
Cr+++Peptide - Laboda, H.M., Raymond E. Vanderlinde, and F.J. Kayne. "Purification of a Naturally-Occurring Chromium Peptide from Human Urine", presented at 1982 American Association for Clinical Chemistry National Meeting, 1983.
Box 3 Folder 20
Symposium on the Use and Misuse of Laboratory Tests, Valley Forge, Pennsylvania, October 28, 1983 - program and Raymond E. Vanderlinde's notes, 1983.
Box 3 Folder 20b
Accuracy Workshop - "Accuracy as an Achievable Goal in Clinical Laboratories" (American Association for Clinical Chemistry workshop co-taught by Raymond E. Vanderlinde.), Washington, D.C., 1984.
Box 3 Folder 21
Task Force - Licensure (of Clinical Chemists), 1984.
Box 3 Folder 22
National Committee for Clinical Laboratory Standards (NCCLS) - Enzymes, undated.
Box 3 Folder 23
American Association for Clinical Chemistry - 1985 Award for Outstanding Contributions of Service to the Profession of Clinical Chemistry - correspondence and CVs (Awarded to Raymond E. Vanderlinde.), 1985.
Box 3 Folder 24
Symposium on the Clinical Laboratory: Prospects for the Future, Philadelphia, Pennsylvania, March 8, 1985 - program and Raymond E. Vanderlinde's notes, 1985.
Box 3 Folder 25
Beckman Conference: "Diabetes Milletus - From Theory to Therapy", Aspen, Colorado, January 27-29, 1986, 1986.
Box 4 Folder 1
Commission on Accreditation in Clinical Chemistry (COMACC) - correspondence, 1987-1994.
Box 4 Folder 2
American Association for Clinical Chemistry - Government Affairs: Clinical Laboratory Improvement Amendments of 1988 (CLIA) - periodic reports and reviews, 1988, 1992-1993.
Box 4 Folder 3
Academy of Clinical Laboratory Physicians and Scientists (ACLPS) - correspondence, re: ACLPS 25th Anniversary, 1990-1991.
Box 4 Folder 4
Final Report - Task Force on Career Development, 1992.
Box 4 Folder 5
Vanderlinde - Abstracts Submitted, 1977-1980.
Box 4 Folder 6
Vanderlinde - Continuing Education, 1953-1960, 1970-1987.
Box 4 Folder 7
Vanderlinde - CV, 1990.
Box 4 Folder 8
Vanderlinde - Preprints and Reprints, 1950-1969.
Box 4 Folder 9
Vanderlinde - Preprints and Reprints, 1970-1979.
Box 4 Folder 10
Vanderlinde - Preprints and Reprints, 1980-1985.
Box 4 Folder 11
Vanderlinde - Preprints and Reprints, 1986-1989.
Box 4 Folder 12
Vanderlinde - Preprints and Reprints, 1990-1998.
Box 4 Folder 13
Vanderlinde - "A Century of Health Care and Medical Education from the Viewpoint of a Clinical Chemist" (Raymond E. Vanderlinde's history of clinical chemistry.), 2002.
Box 4 Folder 14
Clinical Chemistry Instrumentation 1 - manuals and technical ads - AGA, Aminco, Bausch & Lomb, Beckman, Dade, Hycel, undated.
Box 4 Folder 15
Clinical Chemistry Instrumentation 2 - manuals and technical ads - Pfizer, Sigma, Technicon, undated.
Box 4 Folder 16
Clinical Chemistry Instrumentation 3 - manuals and technical ads - TransAc, Upjohn, Warner-Chilcott, Warner-Lambert, Weisberg (including Weisberg Tri-Slide), Wellcome, Worthington, undated.
Box 4 Folder 17

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